Science, March 20, 2009

Cover
Movement trajectories, each recorded during a
1-hour time period, for rats with brain lesions that reduce dopamine
signaling. These animals serve as a model of Parkinson's disease and
display severe difficulty in initiating movements, as illustrated by
the white trajectories (on black background) showing limited
locomotion. Black trajectories (on white background) illustrate the
recovery of locomotive activity induced by electrical stimulation of
the dorsal columns of the spinal cord.

Rewiring Faulty Circuits in the Brain
A wide range of
neuropsychiatric disorders seems to respond to deep brain
stimulation--but how does it work, and where will it lead?

A Lifetime of Work Gone to Waste?
One scientist who
helped lead the effort to characterize the Yucca Mountain nuclear waste
repository talks about the latest setback.

Exxon Valdez Turns 20
Twenty years ago this
week, the worst oil spill in U.S. history struck Alaskan waters.
Researchers are still asking: Has the ecosystem recovered?

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