Science, April 3, 2009

Cover
QuteMol-rendered image of human rhinovirus 3
(Protein Data Bank ID: 1rhi) illustrating virion topography. Red, blue,
and yellow denote the three major surface capsid proteins; examples of
RNA regional motifs are colored according to predicted base-pairing
fidelity. Sequence diversity within the major surface proteins
contributes to the wide range of immunogenic serotypes characteristic
of the "common cold."
On the Origin of Flowering Plants
Which plant was the mother of all angiosperms? In the fourth essay in Science's
series in honor of the Year of Darwin, Elizabeth Pennisi discusses
efforts to answer Darwin's question about how flowering plants
diversified and spread so rapidly across the globe.

Cold Equations
Far from his cozy office in landlocked Utah, a mathematician grapples with the secrets of polar sea ice.

Trouble on the Final Frontier
NASA's scientific
missions have enjoyed spectacular success. But significant cost
overruns and launch delays jeopardize future missions.

Automating Science
Computers with intelligence can
design and run experiments, but learning from the results to generate
subsequent experiments requires even more intelligence.

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